Mesalamine: A Key Treatment for Ulcerative Colitis and Inflammatory Bowel Disease
What Is Mesalamine?
Mesalamine (also known as 5-aminosalicylic acid or 5-ASA) is an anti-inflammatory medication used primarily to treat ulcerative colitis and other forms of inflammatory bowel disease (IBD). It works by reducing inflammation directly in the lining of the colon, helping to alleviate symptoms like diarrhea, bleeding, and abdominal cramping.
Mesalamine is available in oral, rectal, and topical forms. At King’s Pharmacy and Compounding Center, we offer compounded versions of Mesalamine, including suppositories and enemas, which can be tailored to the severity and location of inflammation.
How Mesalamine Works and Who It Helps
Mesalamine targets inflammation locally within the gastrointestinal tract without being significantly absorbed into the bloodstream. This targeted action makes it ideal for treating mild to moderate flare-ups of ulcerative colitis or maintaining remission in patients with chronic IBD.
Compounded rectal preparations are especially useful for patients with distal ulcerative colitis or proctitis, where direct application ensures rapid, effective relief with fewer systemic side effects.
“Mesalamine is a cornerstone of IBD treatment—reducing flare-ups and helping patients reclaim quality of life.”
Compounded Mesalamine Options at King’s Pharmacy
Our pharmacy compounds:
- Mesalamine suppositories for rectal inflammation
- Mesalamine enemas for left-sided colitis
- Customized doses and preservative-free formulas
This flexibility allows providers to treat hard-to-reach areas of inflammation or create formulations for patients who cannot tolerate oral therapy.
In collaboration with gastroenterologists, we ensure accurate dosing and customized treatment plans that match each patient’s needs and disease progression.
FAQs About Mesalamine
Yes. When formulated correctly by a licensed compounding pharmacy, compounded Mesalamine can provide equivalent or improved local relief, especially for proctitis or rectal flare-ups.
Most patients begin to see improvement in symptoms within 1 to 3 weeks, depending on the delivery method and condition severity.
Mesalamine is generally well-tolerated. Mild side effects may include rectal irritation or cramping. Systemic side effects are rare with rectal administration.
Yes. It is commonly prescribed for both active treatment and maintenance therapy in ulcerative colitis. Long-term use under medical supervision is considered safe.
